科研项目: (1) 国家自然科学基金, 面上项目, 22574147, 二维亚纳米通道外表面传感界面工程及疏水-电荷协同离子信号增强机制, 2026-01-01 至 2029-12-31, 50万元, 在研, 主持 (2) 国家自然科学基金, 重大项目, 22090053, 纳米孔道单细胞单分子原位测量研究, 2021-01-01 至 2025-12-31, 376万元(个人到账经费72万元), 结题,学术骨干 (3) 国家自然科学基金, 面上项目, 21974126, “内表面探针”和“外表面探针”对固态纳米孔道检测性能的影响研究, 2020-01-01 至 2023-12-31, 65万元, 结题,主持 (4) 国家自然科学基金委员会, 青年科学基金项目, 21605053, 炭/氧化硅纳米检测平台的构建及在核酸分子组装密度精确调控应用, 2017-01-01 至 2019-12-31, 20万元, 结题, 主持 (5) 科学技术部, 战略性国际科技创新合作重点项目, 2018YFE0206900, 基于纳米孔芯片与手持式穿刺机器人的早期前列腺癌诊断技术研究, 2021-01 至 2023-12, 882万元, 结题, 参与 (6) 浙江省自然科学基金, 一般项目, Y19B030001, 纳米PDMS润滑涂层开发及抗海洋生物污损性能研究, 2019-01 至 2021-12, 10万元, 结题, 主持 (7) 广东省基础与应用基础研究基金, 面上项目,基于外表面核酸功能化过的固态亚纳米孔道测量技术,2025-01至2027-12,10万元,在研,主持 论文: (1) Mao, H.; Peng, S.; Li, Y.; Ye, C.; Du, Q.; Yin, T.; Gao, P.*; Polydopamine-Functionalized 2D Sub-Nanochannels for Efficient and Diverse Multi-Stimuli Responsive Ion Transport Sensing. Anal. Chem.2026. just accepted. (中科院1区) (2) Wu, X.; Chen, Y.; Wang, D.; Pu, S.; Du, Q.; Gao, P.*; Balancing switching and transient response for ion gating in field-effect nanofluidic transistors. Chin. Chem. Lett.2025, 111623. (中科院1区) (3) Wu, X.; Chen, Y.; Wang, X.; Si, Z.; Du, Q.; Gao, P.*; Dual Ionic Signal Detection: Modulation of Surface Charge of Nanofluidic Iontronics by Dual-Split Gate Voltages. Anal. Chem.2025, 97(5), 2658-2666. (中科院1区) (4) Si, Z.; Xu, H.; Lin, M.; Jiang, Y.; Du, Q.; Ma, H.; Liang, H.; Gao, P.*; Xia, F. Polydopamine-Induced Modification on the Highly Charged Surface of Asymmetric Nanofluidics: A Strategy for Adjustable Ion Current Rectification Properties. Anal. Chem.2022, 94, 2493-2501. (中科院1区) (5) Ma, Q.; Li, Y.; Wang, R.; Xu, H.; Du, Q.; Gao, P.*; Xia, F. Towards Explicit Regulating-ion-transport: Nanochannels with Only Function-elements at Outer-surface. Nat. Commun.2021, 12, 1573. (中科院1区) (6) Gao, P.; Wang, D.; Che, C.; Ma, Q.; Wu, X.; Chen, Y.; Xu, H.; Li, X.; Lin, Y.; Ding, D.; Lou, X.; Xia, F. Regional and Functional Division of Functional Elements of Solid-State Nanochannels for Enhanced Sensitivity and Specificity of Biosensing in Complex Matrices. Nat. Protoc.2021, 46, 4201-4226. (中科院1区) (7) Wu, X.; Li, Y.; Xu, H.; Chen, Y.; Mao, H.; Ma, Q.; Du, Q.; Gao, P.*; Xia, F. Exponential Increase in an Ionic Signal: A Dominant Role of the Space Charge Effect on the Outer Surface of Nanochannels. Anal. Chem.2021, 93, 13711-13718. (中科院1区) (8) Liu, T.; Wu, X.; Xu, H.; Ma, Q.; Du, Q.; Yuan, Q.; Gao, P.*; Xia, F. Revealing Ionic Signal Enhancement with Probe Grafting Density on the Outer Surface of Nanochannels. Anal. Chem.2021, 93, 13054-13062. (中科院1区) (9) Ma, Q.; Liu, T.; Xu, R.; Du, Q.; Gao, P.*; Xia, F. Revealing the Critical Role of Probe Grafting Density in Nanometric Confinement in Ionic Signal via an Experimental and Theoretical Study. Anal. Chem.2021, 93(4), 1984-1990. (中科院1区) (10) Wu, X.; Che, C.; Wang, X.; Du, Q.; Liang, H.; Gao, P.*; Xia, F. Ionic Signal Enhancement by the Space Charge Effect through the DNA Rolling Circle Amplification on the Outer Surface of Nanochannels. Anal. Chem.2021, 93, 16043-16050. (中科院1区) (11) Gao, P.; Ma, Q.; Ding, D.; Wang, D.; Lou, X.; Zhai, T.; Xia, F.* Distinct Functional Elements for Outer-surface Anti-interference and Inner-wall Ion Gating of Nanochannels. Nat. Commun.2018, 9, 4557. (中科院1区) (12) Gao, P.; Hu, L.; Liu, N.; Yang, Z.; Lou, X.; Zhai, T.; Li, H.; Xia, F. Functional “Janus” Annulus in Confined Channel. Adv. Mater.2016, 28(3), 460-465. (中科院1区) 专利: (1) 高鹏程; 王大贵; 夏帆; 一种抗污染涂层材料的制备方法, 2019-03-01, 中国, ZL201810987658.4 (专利) 授权 (2) 夏帆; 高鹏程; 程洪利; 一种表面修饰的纳米通道膜及其制备方法与应用, 2019-8-30, 中国, ZL20161012913.8 (专利) 授权 (3) 王大贵; 夏帆; 高鹏程; 一种润滑涂料及其制备方法, 2020-09-29, 中国, ZL201910702286.0 (专利) 授权 (4) 高鹏程; 陈雅捷; 吴晓庆; 具有疏水性二维孔道的氧化石墨烯复合薄膜及其制备方法, 2021-12-31, 中国, ZL202111671195.9 (专利) 授权 (5) 高鹏程; 吴晓庆; 陈雅捷; 一种二维亚纳米孔道检测体系、核酸分子检测装置及其应用,2022-11-11,中国,CN202210980160.1 (专利) 授权 |